Meet the speakers - Lecture Series
Guest Speakers in the Winter Semester 2020/21
|December 10th, 2020
|Prof. Dr. Dr. Melanie Königshoff, University of Pittsburgh, Pennsylvania
A path to lung regeneration
Abstract: This presentation is focused on novel concepts and approaches for lung regeneration and will provide critical translational information about our knowledge of lung structural changes over the lifespan, how chronic lung disease develop and novel targets and tools to initiate lung regeneration. The presentation will highlight recent findings on progenitor cell function and regulation by developmental pathways, and human tissue based models for translational studies will be introduced.
Meeting-ID: 943 0107 1024
|December 15th, 2020
|Dr. Sabine Bauer, Walther-Straub-Institute, LMU Munich
„From Hit to Lead“
Concepts in Drug Discovery and Development
An introduction to the multi-parameter optimization process of drug discovery and development with a lecture and lab component. A major goal of Pharmacology research is to discover novel therapeutic strategies for the treatment of disease. The presentation will cover the process of drug discovery and development, introduction to different aspects of basic and applied sciences involved in drug candidate identifications, and how candidate molecules are made into drugs and drug products in the clinic and market.
Meeting-ID: 971 2049 4044
|December 18th, 2020
|Dr. Peter Reinemer
„Introduction to X-ray Crystal Structure Analysis of Proteins“
Abstract: Modern textbooks of Biochemistry and Pharmacology provide a lot of information about protein structure and protein-ligand complexes and also modern methods in drug discovery make signifcant use of structural information. This method seminar intends to provide knowledge about the process how to determine protein and protein-ligand structures from protein crystals by X-ray diffraction methods. It is adressed to medicine and science students who want to gain an introductionary insight into the method and it covers all steps required to complete an analysis, including protein purification, protein crystalliaztion, X-ray diffraction and data collection, phase problem and structure solution, and model building and refinement. It concludes with some interesting structure examples originating from the scientific work of the author to illustrate the impact of structural studies for the understanding of protein structure, ligand binding and structure guided drug discovery.
Meeting-ID: 955 7546 8738